| E | Earl; East; England, used usually of titles of honour created in the peerage or baronetage of England |
| Ebor | Eboracensis (of York) |
| EC | Etoile de Courage (Canada); European Community; European Commission; Emergency Commission |
| ECGD | Export Credits Guarantee Department |
| ECSC | European Coal and Steel Community |
| ED | Efficiency Decoration; Doctor of Engineering (US); European Democrat |
| EDC | Economic Development Committee |
| Edin | Edinburgh |
| edn | edition |
| edtl | editorial |
| educ | educated |
| Educn | Education |
| EEC | European Economic Community |
| EEF | Engineering Employers' Federation; Egyptian Expeditionary Force |
| EEIBA | Electrical and Electronic Industries Benevolent Association |
| EETPU | Electrical Electronic Telecommunication & Plumbing Union |
| EFTA | European Free Trade Association |
| EI | East Indian; East Indies |
| EICS | East India Company's Service |
| EIS | Educational Institute of Scotland |
| EIU | Economist Intelligence Unit |
| EMBO | European Molecular Biology Organisation |
| EMS | Emergency Medical Service |
| Engrg | Engineering |
| ENO | English National Opera |
| ENSA | Entertainments National Service Association |
| EO | Executive Officer |
| EOC | Equal Opportunities Commission |
| EP | European Parliament |
| EPSRC | Engineering and Physical Sciences Research Council |
| ER | East Riding; Eastern Region (British Railways) |
| ERA | Electrical Research Association |
| ERD | Emergency Reserve Decoration (Army) |
| ESA | European Space Agency |
| ESL | English as a Second Language |
| Esq | Esquire |
| ESRC | Economic and Social Research Council; Electricity Supply Research Council |
| est | eldest |
| ESU | English-Speaking Union |
| ETUC | European Trade Union Confederation |
| EU | European Union |
| exec | executive |
| Expdn(y) | Expedition(ary) |
| Extrdy | Extraordinary |